CORDIS Project
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This project aims to improve gene therapy for cardiovascular diseases by developing novel adeno-associated virus serotypes that can evade immune responses. The goal is to create effective vectors for targeted treatment and personalized medicine.
Cardiovascular diseases remain the primary cause of morbidity and mortality in the western countries.
Pharmacological treatment improves survival and quality of life, but does not reverse disease progression.
Gene therapy could fill this void, owing to its ability to treat the underlying cause.
Adeno-associated viruses (AAV) emanated in the past decade as potent vectors, owing to their tropism for specific tissues, their low immunogenicity, their lack of pathogenicity and their ability to sustai…
UNIVERSITATSKLINIKUM HEIDELBERG
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