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The IGNITE project investigates how environmental factors influence cancer initiation, particularly in pancreatic cancer, by examining the interactions between inflammation and genetic predisposition. It aims to identify epigenetic markers and develop new methods to understand and manipulate immune responses in cancer…
The gene-environment interaction paradigm has long provided a framework for understanding the contribution of environmental cues to cancer initiation.
However, recent perspectives reveal that even amongst genetically identical cells, responses to environmental variation can be remarkably diverse.
When and how pathogenic gene-environment interactions effectively ignite cancer remains ambiguous.IGNITE aims to explain what drives cancer initiation beyond genetics by dissecting (mal)adaptive respons…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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