CORDIS Project
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This project investigates IgG4-autoimmune diseases, which affect various organs and often resist current treatments. By exploring genetic factors and immune responses, the project aims to develop new therapeutic targets and a humanized mouse model for testing innovative therapies, including immune-apheresis.
IgG4-autoimmune diseases (IgG4-AID) are rare but collectively correspond to a significant group of devastating diseases affectingmany different organs, e.g. skin, brain, nerves and kidney in patients that often remain unresponsive to current treatments.
IgG4-AIDhave commonalities indicating a shared underlying immunopathogenesis that make a joint approach to identify new therapeutictargets and test new treatment strategies feasible and necessary.
We hypothesize that genetic risk factors and a dy…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN
Germany, Lübeck
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Türkiye, Istanbul
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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