CORDIS Project
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This project investigates the role of Immunoglobulin E antibodies and their associated cells in defending against antibiotic-resistant bacterial infections. It aims to understand how these immune components can enhance host defense mechanisms, particularly in response to toxins produced by pathogens.
In combination, Immunoglobulin E antibodies (IgEs) and IgE effector cells, most importantly mast cells (MCs) and basophils, are best known for their disease-causing roles in allergic conditions. MCs can also participate in innate host defense against pathogens and toxins.
In contrast, physiologic functions of IgEs that benefit the host are still elusive.
Dr.
Philipp Starkl led a recent study reporting the critical role of IgEs and IgE effector cells in a beneficial type 2 immune response against…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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