CORDIS Project
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This project investigates the role of interleukin-22 in tissue repair and cancer development in the intestines. By analyzing the regulation of this factor, it aims to uncover insights into the relationship between gut health and cancer risk.
Chronic mucosal inflammation and tissue damage predisposes patients to the development of colorectal cancer.
One hypothesis is that the same factors important for wound healing, if left unchecked, also promote tumorigenesis.
Tight control by a sensor of tissue damage should induce these factors to promote tissue repair, while limiting their activity to prevent development of cancer.IL-22, a prototypical tissue repair factor, plays an important role in a wide variety of intestinal disease includi…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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