CORDIS Project
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This project aims to uncover the molecular mechanisms regulating translesion DNA synthesis during DNA damage repair. By identifying novel proteins involved in this process, it seeks to enhance our understanding of how cells maintain genome integrity under stress.
Here, I propose to unravel the molecular mechanisms that regulate TLS during DNA damage bypass through advanced complementary approaches.Thousands of DNA damaging insults are inflicted daily upon the genomes of all living cells.
If left unrepaired, these lesions can be life-threatening for organisms as they alter the content and organization of the genetic material.
To overcome this constant challenge, cells are equipped with a global DNA damage response that impacts on diverse cellular processe…
KOBENHAVNS UNIVERSITET
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