CORDIS Project
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This project investigates the role of gut microbiota in metabolic diseases, particularly type 2 diabetes. It aims to identify inhibitors of a specific enzyme to reduce a harmful metabolite linked to insulin resistance, potentially leading to new diabetes treatments.
The gut microbiota has been associated with metabolic diseases, such as type 2 diabetes.
In my ERC consolidator award we demonstrated that the gut microbiota is altered following bariatric surgery and that the altered microbiota may be directly linked to some of the metabolic improvements observed following surgery.
Interestingly, improved metabolism was associated with altered metabolite production capacity from the microbiota and we observed that a metabolite, imidazole propionate, was reduced…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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