CORDIS Project
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This project aims to explore how poxviruses, specifically Molluscum Contagiosum virus, modulate human immune responses. By identifying viral sequences that affect immunity, it seeks to develop new immunotherapeutics to combat infectious diseases.
Infectious diseases kill 16 million people world-wide each year.
Understanding how the immune system functions to sense and fight pathogens is essential for the development of novel therapeutics.
Poxviruses have evolved a wide-spectrum of open-reading frames (ORFs) encoding immunoregulators which bind host proteins and disrupt the antiviral immune response.
These ORFs are acquired from the host and are incorporated into the terminal regions of the viral genome.
The acquisition of this extensive…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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