CORDIS Project
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This research focuses on developing new vaccines against Salmonella Typhi, a major cause of typhoid fever. By identifying gene expression patterns associated with vaccine protection, the project aims to accelerate the development of effective vaccines.
Salmonella enterica serovar Typhi (S.
Typhi) is a major human pathogen causing approximately 22 million new infections and 600,000 deaths annually posing a significant challenge for strategies to control the infection in endemic areas.
Current vaccines are of limited efficacy and cannot be used in young children.
Development of new alternatives has stalled due to the high costs associated with performing large field trials as no reliable correlates of protection exist.
Using a novel human challe…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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