CORDIS Project
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This project investigates embryonic stem cells to identify specific markers for endocrine progenitor cells that can differentiate into insulin-producing cells. The research aims to enhance understanding of pancreatic cell development and potential applications in treating diabetes.
Embryonic stem (ES) cells are derived from the inner cell mass (ICM) of blastocyst-embryo stage.
The potential of ES cells to differentiate in all kind of tissues, opens the possibility for future promising approaches, as genetic therapy and/or cell replacement, to treat many diseases, including type1 diabetes.
Although several scientific groups have reported the successful differentiation of mouse ES cells to insulin producing cells, the therapeutic benefits have yet to be achieved.
Recently, i…
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