CORDIS Project
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This project aims to understand the mechanisms of tryptophan hydroxylase, a key enzyme in neurobiology, using advanced computational and spectroscopic techniques. Insights gained will aid in the design of targeted drugs for neurological disorders.
Metalloenzymes play crucial role in neurobiology and therefore they are very important target for drug design for treatment neuropathological processes.
In order to make new specific and effective drugs it is crucially important to understand the structure and functions of their drug targets.
In this Outgoing Marie Curie Fellowship application we propose combined computational/spectroscopic investigation of the enzyme mechanism of tryptophan hydroxylase – a pterin-dependent non-heme containing i…
UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE
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