CORDIS Project
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This project aims to understand the accumulation of senescent cells in aging and their role in age-related diseases, particularly in vascular tissues. By studying the interaction between these cells and the immune system, the research seeks to identify new therapeutic strategies for targeting senescent cells.
Cell senescence plays a paradoxical but important role in physiology; it protects organisms against cancer but also contributes to age-related loss of tissue function.
Senescent cells accumulate during ageing, particularly at sites of age-related pathologies such as vascular tissue, contributing to fibrotic cardiovascular disease , .
Therefore, the aim of this research is to understand why senescent cells accumulate later in life for the purpose of identifying potential therapeutic strategies fo…
ASTON UNIVERSITY
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