CORDIS Project
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ICoMICS focuses on enhancing the immune response against solid tumors by developing a predictive modeling platform. It combines 3D tumor organoids and advanced simulations to study how therapeutic immune cells interact with cancer cells and their environment, aiming to create innovative immunotherapies for lung, liver,…
The immune system consists of a collection of cells with a high ability to migrate that work together to remove harmful foreign material from the body.
Each immune cell can migrate between tissues, fulfilling specific functions in different microenvironments.
However, this immune-surveillance response is not very effective in those tissues with a high non-physiological stiffness and a significant level of residual stresses, which are characteristics of solid tumors.
Understanding the mechanisms…
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