CORDIS Project
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This project develops a computational model that combines blood flow dynamics and arterial wall mechanics to better understand atherosclerosis. It focuses on how low-density lipoprotein transport contributes to the disease's progression.
Atherosclerosis, a disease of large- and medium-size arteries, is the major cause of death in most of the Western world.
The blood flow and its interaction with the arterial wall deformation are considered to play a significant role in the pathobiological mechanisms (i.e. LDL concentraton) involved in the process of atheroma formation.
Therefore, a unified computational model framework is proposed herein, which integrates blood flow dynamics and arterial wall mechanics, and based on the findings…
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