CORDIS Project
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This project develops an intestine-on-a-chip device using primary human intestinal cells to study interactions between gut bacteria and the intestinal barrier. The innovative model simulates in vivo conditions to better understand disease mechanisms and potential therapeutic targets.
The small intestine forms a barrier that protects us against the outer world.
Here commensal bacteria are tolerated while pathogens are effectively fought off.
Occasionally, however, pathogenic bacteria colonize the intestine causing different diseases, which constitute a huge burden worldwide.
The ability to study interactions of pathogenic bacteria with the intestine will provide new insights into the disease mechanisms, and new therapeutic targets and ways to prevent disease occurrence.
Curre…
KOBENHAVNS UNIVERSITET
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