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HyperAstroMet explores the metabolic changes in astrocytes, a type of brain cell, in relation to Alzheimer's disease. The project aims to uncover how these metabolic disturbances contribute to neuronal dysfunction and cognitive decline, potentially identifying new therapeutic targets.
Alzheimer's disease (AD) represents a growing public health challenge, with its prevalence steadily increasing profoundly affecting both patients and their families.
Despite extensive research focusing on amyloid-beta and tau as central pathological hallmarks of AD, the crucial role of astrocytic metabolism in neurodegeneration has often been overlooked.
The HyperAstroMet project introduces a novel approach by investigating astrocytic hypermetabolism as a pivotal driver of neuronal hyperexcitabi…
UNIVERSIDAD DE NAVARRA
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