CORDIS Project
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This project focuses on improving radiation treatment for aggressive brain cancers by using advanced imaging techniques to identify hypoxic tumor regions. It aims to deliver targeted radiation doses to these areas, enhancing treatment effectiveness while protecting healthy tissue.
Glioblastoma and skull base chordoma are two of the most aggressive types of brain cancers and have an extremely poor prognosis, with most tumours recurring within months of surgical and chemoradiation treatments.
Recurrence is caused by tumour heterogeneity, as regions of the tumour with different biological properties respond differently to treatment.
Tumour hypoxia (low oxygenation) is the leading cause of resistance to radiotherapy in heterogeneous cancers and is linked to poor patient progn…
POLITECNICO DI MILANO
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