CORDIS Project
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This project focuses on developing a specialized scaffold, called the hydrocup, for the targeted delivery of cells that secrete beneficial cytokines. By ensuring the retention of these cells in specific locations, the hydrocup aims to enhance tissue regeneration and improve outcomes in cell-based therapies, particularl…
Secreted cytokines by transplanted cells can have positive effects such as immunomodulation, angiogenesis and tissue regeneration.
However, transplanted cells are difficult to retain in a specific place to maximize the release of cytokines on site.
Here, we developed a hollow electrospun scaffold with one open and one closed end for the in vivo delivery of cells as ?secretory factories? in a hydrogel, termed the hydrocup.
Because of the closed end, a (cell-laden) hydrogel can easily be dispensed…
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