CORDIS Project
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This project focuses on understanding how hyaluronan affects the growth and differentiation of mesenchymal stem cells. It aims to optimize stem cell expansion for therapeutic applications by controlling hyaluronan levels to maintain stemness and prevent premature aging.
Hyaluronan (HA), a linear polysaccharide in the extracellular matrix (ECM) of higher animals is a key player in tissue remodelling.
Mesenchymal stem cells (MSC) exhibit multipotential differentiation capacities and are therefore of high clinical importance.
Novel cell therapeutic approaches based on the differentiation and regeneration potential of MSC have been developed and successfully applied in numerous clinical studies.The stemness of MSC is described by their ability to form colonies and…
UNIVERSITAET INNSBRUCK
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