CORDIS Project
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This project investigates the genetic basis of growth regulation in humans, particularly focusing on conditions like primordial dwarfism. It aims to identify genes involved in brain and body size, contributing to our understanding of developmental biology and potential therapeutic targets.
The greatest differences between mammals are size.
As well, the large evolutionary expansion of the cerebral cortex is a defining feature humans.
Despite this, much remains to be learnt about the developmental and evolutionary factors controlling organ and organism size.
This is in marked contrast to the exquisite detail in which developmental patterning has been defined in model organisms.
The identification of genes for human disorders of extreme growth failure (microcephalic primordial dwarf…
THE UNIVERSITY OF EDINBURGH
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