CORDIS Project
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The project focuses on understanding and targeting leukemic stem cells, which are resistant to current treatments for human myeloid leukemias. By establishing a mouse model that represents various leukemia subtypes, the research aims to identify new markers and treatment strategies to improve patient outcomes.
Human myeloid leukemias are life-threatening disorders.
Although with current therapies the bulk of the tumor is readily eradicated, it is particularly the rare population of leukemic stem cells (LSCs) that is relatively quiescent and is very difficult to target.
As a consequence, relapse of the disease occurs frequently resulting in poor survival rates.
Nevertheless, remarkable differences do exist between subsets of patients.
It is important to realize that leukemias are rather heterogeneous d…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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