CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the dynamic behavior of the Hsp90 chaperone protein, crucial for proper protein folding and cancer cell proliferation. Using advanced techniques like nuclear magnetic resonance spectroscopy, the study aims to reveal how Hsp90 interacts with client proteins, such as the glucocorticoid receptor,…
Proper protein folding is essential for cellular homeostasis.
Cells employ a large array of chaperones to ensure protein adopt the proper conformation.
Hsp90 is an important chaperone and comprises of 1-2% of all protein is eukaryotic cells.
Additionally, Hsp90 is upregulated in cancerous cells to facilitate fast proliferation.
There are several X-ray crystal structures available for Hsp90 free in solution and interacting with its target proteins.
This combined with small angle x-ray/neutron…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
