CORDIS Project
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This project explores the link between chronic inflammation and cancer development, focusing on the PKC/NR2F6 signaling pathway in immune cells. By identifying molecular signatures related to tumor risk, it aims to enhance therapeutic strategies for lung cancer and improve immune responses against tumors.
Because of its biological complexity, cancer is still poorly understood.
Chronic inflammation has been shown, both experimentally and epidemiologically, to be a predisposition to, and also an inseparable aspect of clinically prevalent cancer entities.
Therefore, a detailed understanding of both tumour and immune cell functions in cancer progression is a prerequisite for more successful therapeutic startegies.
My team was the first to reveal the lymphocyte-intrinsic PKC/NR2F6 axis as an essential…
MEDIZINISCHE UNIVERSITAT INNSBRUCK
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