CORDIS Project
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This project explores how gut bacteria influence the immune system and the renewal of intestinal cells. By examining both beneficial and harmful microbes, the research aims to understand their roles in maintaining gut health and developing new therapeutic strategies.
The molecular cross talks occuring at the interface between the intestinal epithelium and bacterial flora will be studied at two levels : (i) how commensals and pathogens affect innate immune signalling, thereby leading to tolerance of the resident microbiota, and inflammatory rejection of the pathogens.
The theme of commensals and pathogens regulating this innate response, particularly how they respectively strengthen or weaken the network of humoral and cellular epithelial defense systems will…
INSTITUT PASTEUR
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