CORDIS Project
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The project investigates programmed cell death mechanisms in unicellular relatives of animals to understand their evolution and significance in multicellularity. By analyzing specific proteins involved in cell death, the research aims to uncover ancestral traits that contributed to the emergence of apoptosis in animals…
Programmed cell death (PCD) is an essential function in multicellular organisms; it regulates normal development, responses to cell damage, and cell turnover.
Accordingly, the PCD machinery present in the unicellular ancestors of animals was likely critical to the emergence of the complex multicellularity found in extant animals.
However, we lack a full understanding of the PCD repertoire in the unicellular relatives of animals, and whether that ancestral repertoire underwent significant changes…
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