CORDIS Project
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This project investigates how cancer cells behave in clusters and their surrounding environment, focusing on their ability to move through dense tissues. By developing a model to predict when cancer cells can overcome physical barriers, the research aims to improve understanding of tumor progression and enhance surgica…
Since decades the bulk of cancer research focusses on the genetic and molecular level.
To complement this knowledge, I will focus on the collective behaviour of cancer cells in cell clusters and in the extracellular matrix (ECM).Conventional cancer research tackles issues like genetic changes, signalling pathways or intracellular mechanisms, I want to answer the question:
When is a cancer cell jammed or when can it overcome the yield stress to actively “flow” in a dense microenvironment (ME)? I…
UNIVERSITAET LEIPZIG
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