CORDIS Project
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This project investigates the role of protein histidine phosphorylation in obesity and metabolic disorders. It aims to understand how changes in histidine phosphorylation affect insulin sensitivity and glucose metabolism in various tissues, potentially leading to better treatments for obesity-related conditions.
Histidine PhosPhorylation and Obesity Protein histidine phosphorylation is a poorly characterized post-translational modification.
Its importance in mammalian cellular function is emerging from the discovery of histidine kinases and phosphatases and their substrates.
Recently, histidine phosphorylation has been involved in heart failure and cancer.
Obesity and type 2 diabetes remain challenging disorders due to growing prevalence around the world and poorly efficient treatments.
Regarding metab…
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