CORDIS Project
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The HIPShot project aims to uncover the biology of Hepatitis B virus infection by identifying host factors critical for the virus's life cycle. Utilizing advanced tissue culture models and screening techniques, it seeks to discover potential drug targets for effective antiviral therapies.
Hepatitis B virus (HBV) is a major global health problem resulting in progressive liver disease, including cirrhosis and hepatocellular carcinoma – the second leading cause of cancer death worldwide.
Although HBV structure and genome have been characterized, key aspects of the viral life cycle remain poorly understood because of the lack of a robust HBV infectious tissue culture system.
Moreover, despite the development of a safe and efficient vaccine, over 240 million people are chronically inf…
UNIVERSITE DE STRASBOURG
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