CORDIS Project
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This project aims to develop a technology for selectively inhibiting specific neural pathways from the hippocampus to understand their role in anxiety behavior. By manipulating neurotransmitter release in targeted brain areas, it seeks to clarify how different brain circuits contribute to anxiety.
The brain structures and neural circuits regulating anxiety behavior are poorly understood.
The hippocampus contribute to anxiety via its role in the behavioral inhibition system and descending outputs via the fornix to the septum and frontal cortex are thought to be critical to this modulating effect.
However, it is not clear what the contributions of septal and frontal cortical outputs are to anxiety because, until now, no manipulations were available to selectively inhibit these pathways.
Her…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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