CORDIS Project
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This project investigates Kainate receptors in the brain, focusing on their role in neuronal function and potential involvement in brain diseases. It aims to develop pharmacological and genetic tools to study these receptors in granule cells, particularly their role in synaptic plasticity and memory.
Kainate receptors (KARs) are often regarded as the last frontier of glutamate receptor research, since much less is known about their physiological roles compared with that of the other glutamate receptor subtypes.
This field of research is very important not just because of the unique role that KARs play in neuronal function, including specific forms of synaptic plasticity, but because of the increasing evidence that KARs are involved in a plethora of brain diseases and that KAR antagonists are…
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