CORDIS Project
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This research focuses on the role of acetylcholine in hippocampal function and information processing. By using advanced techniques, it aims to understand how cholinergic modulation affects neuronal activity and cognitive performance in mice.
Acetylcholine released by cholinergic neurons in the basal forebrain is a critical component of the modulatory cocktail governing the emergence, stabilization and reorganization of cortical ensembles of co-active neurons representing the environment.
In the hippocampus, ACh renders the state of the network optimal for the acquisition of novel information.
Deterioration of cholinergic modulation leads to severe deficits in hippocampal function manifested as debilitating cognitive impairments.
Des…
HUN REN KISERLETI ORVOSTUDOMANYI KUTATOINTEZET
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United States, NEW YORK
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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