CORDIS Project
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This project investigates the role of hypoxia and cancer-associated fibroblasts in colorectal cancer progression. By studying the effects of hypoxia on these fibroblasts, it aims to uncover new therapeutic targets to improve treatment outcomes.
Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide.
Despite significant advancements in understanding CRC pathogenesis, the clinical prognosis of CRC patients is still poor due to metastasis dissemination.
Cancer progression is often associated with the presence of cancer-associated fibroblasts (CAFs) in the tumor microenvironment that regulate processes such as extracellular matrix (ECM) deposition and repression of the immune response.
The establishment of a hypox…
UNIVERSITE DU LUXEMBOURG
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Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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