CORDIS Project
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This project investigates collective cancer cell invasion, focusing on how different cancer cell types interact during movement. By combining live cell imaging and mathematical modeling, it aims to enhance understanding of tumor dynamics and improve strategies to combat cancer metastasis.
Recent live cell imaging studies have demonstrated that cancer cells invade either as single cell or as cell group retaining cell-cell adhesion.
In contrast to the well-documented single cell movement, little is known about collective cancer cell invasion.
Given that a single tumour tissue contains various types of cancer cells and the collective movement of cancer cells is sum of the behavior of phenotypically different cells, we hypothesised that intratumour heterogeneity affect collective inv…
THE FRANCIS CRICK INSTITUTE LIMITED
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