CORDIS Project
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This project investigates the biology of hepatitis C virus and its relationship with host proteins to identify potential therapeutic targets. It aims to purify HCV particles from clinical samples and analyze their associated proteins to understand their roles in the viral lifecycle.
The emergence of hepatocellular carcinoma (HCC) has prompted a search for a thorough understanding of the biology of one of its major causative agents, the hepatitis C virus (HCV).
Half of genotype 1 patients, the most numerous in Europe, do not respond to treatment, putting them at risk for cirrhosis and HCC. HCV particles acquire via budding and encapsidation cellular proteins.
There is mounting evidence on several viral species that virion-bound proteins are prone to be involved either at the…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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