CORDIS Project
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This research investigates the relationship between autophagy and the hepatitis C virus. It aims to uncover how the virus inhibits autophagy and utilizes its components for viral genome translation, impacting antiviral responses.
Autophagy is a major intracellular pathway for cellular homeostasis.
It also plays an essential role in antiviral response against diverse pathogens.
Indeed, in addition to the removal of viral protein aggregates from the cells, autophagy is emerging as a key regulator of viral propagation by regulating positively or negatively the secretion of interferon α/β (IFNα/β) and inflammatory molecules, known to be essential to initiate antiviral responses.
However, certain pathogens such as, for exampl…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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