CORDIS Project
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This project investigates the mechanisms underlying temporal lobe epilepsy, focusing on neuronal changes and the transition to seizures. It employs various techniques to analyze neuronal types and factors contributing to epileptic activity.
This proposal focuses on a human disease: epilepsy of the temporal lobe.
This syndrome has a relatively stereotyped history.
Focal seizures emerge, with a delay of several years in the human, after an initial insult that results in neuronal death.
We will use physiology, imaging, anatomy and transcriptomic techniques to ask how an epileptic brain emerges, to define different neuronal cell types in the basal epileptic state and to examine factors associated with the paroxysmal transition to a se…
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
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