CORDIS Project
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This research aims to understand the formation of synapses in the brain, specifically how new connections are made during learning. By using advanced imaging techniques, it will identify the presynaptic neurons involved in newly formed synapses and their role in memory retention.
The formation and elimination of spine synapses can be visualized both in vitro as well as in vivo using advanced imaging techniques.
It is known that the number of dendritic spines changes both during development as well as during the acquisition of new memories.
However, up to now these observations are entirely correlative.
It is unclear if the presynaptic neuron forming a functional contact on a newly formed spine indeed was the one that showed correlated activity with the postsynaptic cell…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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