CORDIS Project
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This project focuses on developing multi-scale heart simulators to improve patient-specific treatments by linking molecular observations to cardiac performance. It aims to characterize the mechanosensing mechanism in heart muscle, potentially enhancing understanding of heart function and related diseases.
Multi-scale heart simulators for patient specific treatments are an important challenge for the development of the health system, but require interdisciplinary interaction of several techniques to link experimental observations at the molecular level to the cardiac performance.
The mechanosensing (MS) mechanism active in the myosin thick filament, recently discovered, is promising for the understanding of several unresolved questions in muscle field, including the molecular basis of the Frank-St…
UNIVERSITA DEGLI STUDI DI PADOVA
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