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This research focuses on the hEag1 ion channel, which is linked to breast cancer. The project aims to develop selective ligands to study the channel's role in cancer progression and explore its potential as a therapeutic target.
The human ether à go-go 1 (hEag1) ion channel, also known as Kv10.1, is a voltage-gated potassium channel that is highly expressed in the brain but remains largely absent in other tissues under healthy conditions.
However, during cancer development, hEag1 is significantly upregulated in various tumours, making it a potential biomarker and therapeutic target.
Its role in cancer, particularly in breast cancer, is still not well understood, which makes exploring hEag1 a critical focus of my researc…
UNIVERSITAT WIEN
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