CORDIS Project
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This project investigates the molecular mechanisms of human excitatory amino acid transporters, which regulate glutamate levels in the brain. By employing multidisciplinary biophysical techniques, the goal is to understand their function and pharmacology, paving the way for new therapeutic strategies to address neurolo…
The paramount importance of human membrane proteins for life contrasts with the lack of understanding of their molecular mechanisms of function and pharmacology.
This project focuses on the molecular mechanisms of one of the most important and medically relevant families of neurotransmitter membrane transporters in the brain, the Human Excitatory Amino Acid Transporter (hEAAT) family.
Glutamate is the main excitatory neurotransmitter in the brain and its extracellular concentration is mainly reg…
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