CORDIS Project
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This project focuses on understanding the role of histone deacetylase 6 in non-small cell lung cancer. By developing a specific mouse model, it aims to explore how this enzyme influences tumor development and resistance to therapies, potentially leading to new targeted treatments for lung cancer.
Lung cancer is a leading cause of cancer deaths in Europe.
Non small cell lung cancer (NSCLC) accounts for nearly 85% of all cases of lung cancer with a five year survival rate of 15%.
Novel targeted therapies are urgently needed to overcome drug resistance and prevent tumour recurrence.
The host supervisor carried out a small molecule screen to identify therapeutics for the treatment of drug-resistant NSCLC. A novel specific inhibitor of histone deacetylase 6 (HDAC6) was discovered.
The molecul…
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United States, NEW YORK
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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