CORDIS Project
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This project focuses on understanding how the Hepatitis C virus enters liver cells and the role of a specific protein, EWI-2wint, in inhibiting this process. By characterizing this inhibition, the research aims to uncover potential therapeutic strategies against Hepatitis C.
There are more than 130 million people infected with Hepatitis C worldwide.
The Hepatitis C virus (HCV) is an enveloped RNA virus targeting liver cells. HCV represents one of the most important pathogens of humans.
It is still not clear how exactly viral entry proceeds.
So far several receptors have been found to play a role in virus entry, among them CD81, SR-BI and Claudin-1.
The recent finding of a negative regulator, EWI-2wint, further complicates the matter.
This protein, which is an Ntermi…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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