CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of adenosine receptors in regulating inflammation and immune responses in type 1 diabetes and islet graft rejection. By identifying specific receptor subtypes, the research aims to develop targeted therapies to protect pancreatic islets from destruction.
Adenosine receptors are expressed on immune cells and other tissues thought to regulate inflammatory events in mammals.
Adenosine receptors, when activated by endogenous ligands or exogenous analogs, may repress inflammatory and immune pathways that lead to the destruction of pancreatic islets in models of type I diabetes and islet graft rejection.
Building on our observations that inosine and NECA, two adenosine receptor agonists, inhibit diabetes and islet graft rejection in non-obese diabetic…
HUN REN KISERLETI ORVOSTUDOMANYI KUTATOINTEZET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
