CORDIS Project
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This project explores the genetic and adaptive mechanisms of tumor invasion in cancer using engineered mouse models. It aims to identify factors that influence invasive growth and develop therapeutic strategies targeting both invasion and angiogenesis.
Acquisition of the hallmark capability for invasion and in turn metastasis is for most human cancers the defining event in progression to life threatening disease.
Its determinants are remarkably complex.
Genetically engineered mice can model human cancers, with tumors arising in specific organs, reflecting onco-genomic and histopathological features of particular tumor types.
This project will use four mouse models to characterize newly implicated determinants of invasive tumor growth.
We ha…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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