CORDIS Project
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This project investigates the role of transposable elements, which are repetitive DNA sequences, in maintaining tissue health and function. By studying these elements in the Drosophila intestine, the research aims to understand their impact on cell types, aging, and diseases like cancer.
Life-long tissue homeostasis requires sustained function of differentiated cell types as well as progenitor cells, which ensure tissue self-renewal.
Little is known about the role that non-genic repetitive DNA sequences play in the maintenance of cellular homeostasis in divers somatic tissues in vivo.
Transposable elements (TEs) are omnipresent, highly repetitive DNA sequences that mobilize and propagate within host genomes.
Though previously thought to be fully repressed in the soma, TEs can be…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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