CORDIS Project
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The GUTPOLAR project focuses on understanding the mechanisms of intestinal absorption related to rare malabsorption diseases. By studying the role of the V0 sector of the V-ATPase in cell polarity and brush border formation, the project aims to identify new therapeutic targets for these disorders using model organisms…
The GUTPOLAR project aims at sustainably reintegrating an Experience Researcher (ER) who will acquire the necessary knowledge and skills to reinforce European research on rare malabsorption diseases.Food absorption relies on the strong polarity of intestinal epithelial cells and the array of microvilli forming a brush border (BB) at their luminal (apical) pole.
Some rare genetic malabsorption disorders, characterized by mispolarized PAR polarity modules and BB structural proteins, are caused by…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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