CORDIS Project
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This project aims to deepen the understanding of inflammatory bowel disease by studying the immune system's role in the intestines. It focuses on characterizing lymphocyte populations and their responses to treatments, with the goal of identifying new therapeutic targets.
Inflammatory bowel disease (IBD) constitutes an increasing global health burden, yet effective treatments are lacking.
Hampering rationale treatment strategies, the human intestinal immune system remains largely unexplored. I have made seminal contributions to the discovery and characterization of innate lymphoid cells (ILCs) (Nat Immunol 2011, 2013 and 2016, Immunity 2012), revealing that in addition to antigen-specific adaptive T cells, innate equivalents play important roles in mucosal immuni…
KAROLINSKA INSTITUTET
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