CORDIS Project
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This project investigates the role of G protein-coupled receptors in mucosal immunity within the gut and airways. By employing advanced imaging and sequencing techniques, it aims to understand immune regionalization and identify potential therapeutic targets for diseases affecting these tissues.
Mucosal immunity is essential to preserve homeostasis and for pathogen control within the gut and the airways.
The emerging dogma of immune regionalization has opened to new questions about which elements drive cell adaptation to different niches, and how this can be targeted to cure diseases.
The intestine and the airways are functionally diverse along their length, and disorders can differentially impact on different mucosal tissue regions.
Mucosa-associated lymphoid tissues (MALTs) are locate…
UNIVERSITA VITA-SALUTE SAN RAFFAELE
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