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The GREAM project focuses on understanding glycyl radical enzymes, which are crucial biological catalysts involved in various metabolic processes. By studying their activation mechanisms, the project aims to provide insights into their structural biology and function.
Glycyl radical enzymes (GREs) are one of the most prominent biological catalysts in both strict and facultative anaerobes.
They are responsible for a broad range of radical-based chemistry and catalyse reactions involved in diverse metabolic pathways such as acid fermentation, DNA synthesis and the anaerobic metabolism of pollutants. GREs are activated by members of the S-adenosylmethionine (SAM) radical family.
Activation of GREs requires the formation of a protein-protein activation complex wi…
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Sweden, Lund
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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