CORDIS Project
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This project focuses on improving stem cell-based therapies for Parkinson's Disease by investigating the differentiation of human embryonic stem cells into mesencephalic dopaminergic neurons. It aims to understand the roles of key transcription factors and gene regulatory networks in this process, utilizing advanced te…
Stem cell-based therapy is an attractive way to treat a panel of as-yet incurable diseases, amongst which is Parkinson’s Disease, caused by the progressive degeneration of mesencephalic dopaminergic (mesDA) neurons.
To make this a reality, efficient and precise differentiation protocols of human embryonic stem cells (hESCs) need to be developed.
While a protocol for differentiation of mesDA neurons exists, little is known about the resulting progenitors’ homogeneity and the mechanisms that contr…
KOBENHAVNS UNIVERSITET
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